HitPredict

Interactor 1: Q6P0J1 (Q6P0J1)
Hairy and enhancer of split 6 (Drosophila) (Hairy-related 13.2) (Transcription cofactor HES-6)
Gene: hes6

Interactor 2: Q9I9K1 (Q9I9K1)
Hairy and enhancer of split related-7 (Her7-protein)
Gene: her7

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	22911291
Identification Methods	anti tag coimmunoprecipitation, solid phase assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0001756 - somitogenesis GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 226 Dr			1 206
+	Dr
		1240380 Q6P0J1_DANRE (1-226): 7.49e-81: 242: 100.00		Q6P0J1_DANRE (12-205): 1.98e-53: 172: 25.35
+	Hs
		1126798 HES1_HUMAN (3-226): 4.5e-61: 194: 23.79		HES1_HUMAN (10-205): 3.56e-57: 183: 20.97
+	Gg
		1251079 Q6XLQ0_CHICK (2-226): 1.47e-56: 183: 24.18		Q6XLQ0_CHICK (9-201): 1.99e-53: 174: 22.00
+	Dm
		1028561 DPN_DROME (15-221): 1.85e-50: 171: 27.32		ESMC_DROME (4-205): 6.43e-57: 180: 24.04
+	Hs
		1126810 HES1_HUMAN (3-226): 4.5e-61: 194: 23.79		HEY1_HUMAN (7-198): 4.49e-45: 153: 26.13
+	Hs
		1126808 HES1_HUMAN (3-226): 4.5e-61: 194: 23.79		HEY2_HUMAN (7-187): 1.94e-43: 150: 24.60
+	Dm
		1175923 DPN_DROME (15-221): 1.85e-50: 171: 27.32		DPN_DROME (9-206): 1.16e-51: 173: 21.33
+	Gg
		1251077 Q6XLP9_CHICK (2-226): 1.86e-53: 175: 23.00		Q6XLP9_CHICK (9-201): 4.73e-51: 168: 21.00
+	Dm
		560179 ESMC_DROME (4-226): 1.56e-52: 170: 23.04		ESM7_DROME (1-205): 1.44e-54: 173: 21.46
+	Dr
		1240381 Q6P0J1_DANRE (1-226): 7.49e-81: 242: 100.00		Q90463_DANRE (3-191): 1.34e-24: 100: 21.33
+	Hs
		1126803 HES1_HUMAN (3-226): 4.5e-61: 194: 23.79		HES6_HUMAN (5-205): 1.1e-42: 144: 23.85
+	Mm
		771401 HES1_MOUSE (3-226): 4.8e-60: 191: 23.99		HES6_MOUSE (5-205): 2.24e-42: 143: 23.50
+	Hs
		1491691 HEY1_HUMAN (12-225): 5.11e-54: 177: 24.20		HEY1_HUMAN (7-198): 4.49e-45: 153: 26.13
+	Hs
		1458602 HEY1_HUMAN (12-225): 5.11e-54: 177: 24.20		HEY2_HUMAN (7-187): 1.94e-43: 150: 24.60
+	Dm
		1175925 DPN_DROME (15-221): 1.85e-50: 171: 27.32		HEY_DROME (10-186): 1.18e-43: 152: 21.20
+	Hs
		1393907 HES6_HUMAN (1-226): 2.13e-53: 172: 48.52		HES6_HUMAN (5-205): 1.1e-42: 144: 23.85
+	Dm
		560166 ESMC_DROME (4-226): 1.56e-52: 170: 23.04		ESM5_DROME (7-205): 3.15e-43: 144: 20.50
+	Dm
		569356 DPN_DROME (15-221): 1.85e-50: 171: 27.32		HAIR_DROME (11-193): 4.46e-41: 143: 23.00