Interactor 1: HES1 (P35428)
Transcription factor HES-1 (Hairy and enhancer of split 1)
Gene: HES1
Interactor 2: HES6 (Q9JHE6)
Transcription cofactor HES-6 (Hairy and enhancer of split 6)
Gene: HES6
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10851137 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hairy_orange~Hairy_orange, HLH~HLH |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0042803 - protein homodimerization activity and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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| + | Hs |   |
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| + | Hs | |
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| + | Dr | |
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| + | Gg | |
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| + | Dm | |
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| + | Dm | |
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| + | Hs | |
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| + | Mm | |
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| + | Dr | |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
