Interactor 1: VATC2 (Q8NEY4)
V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)
Gene: ATP6V1C2

Interactor 2: VATD (Q9Y5K8)
V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D)
Gene: ATP6V1D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0016241 - regulation of macroautophagy
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 427
Hs

1 247
+ Hs
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024