HitPredict

Interactor 1: GRPE2 (Q8TAA5)
GrpE protein homolog 2, mitochondrial (Mt-GrpE#2)
Gene: GRPEL2

Interactor 2: GRPE1 (Q9HAV7)
GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1)
Gene: GRPEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	GrpE~GrpE
Common GO terms	GO:0000774 - adenyl-nucleotide exchange factor activity GO:0001405 - PAM complex, Tim23 associated import motor GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex and 6 others more... GO:0006457 - protein folding GO:0006886 - intracellular protein transport GO:0030150 - protein import into mitochondrial matrix GO:0042803 - protein homodimerization activity GO:0051082 - unfolded protein binding GO:0051087 - protein-folding chaperone binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	225
Hs

1	217

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024