HitPredict

Interactor 1: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 1129
+	Hs
		1272294 PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Hs
		1084354 SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Hs
		516622 PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Hs
		958225 RBM3_HUMAN (5-91): 1.58e-24: 96.3: 29.89		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Hs
		680472 TIA1_HUMAN (3-125): 1.72e-18: 84.3: 18.70		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Zm
		9333 A0A1D6GKL8_MAIZE (9-86): 5.95e-22: 89.8: 26.92		A0A1D6EWB9_MAIZE (2-1101): 0: 1382: 57.34
+	Sc
		376676 PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60		RENT1_YEAST (60-947): 0: 1085: 53.54
+	Hs
		1288634 PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Sc
		376894 PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60		SEN1_YEAST (286-929): 7.8e-159: 523: 25.46
+	Hs
		1084418 SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Hs
		1031468 PABP4_HUMAN (11-196): 1.86e-23: 99.6: 12.37		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Hs
		516699 PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Hs
		958245 RBM3_HUMAN (5-91): 1.58e-24: 96.3: 29.89		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Hs
		963574 TIAR_HUMAN (3-142): 1.74e-18: 84.3: 14.89		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Hs
		789169 PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54		HELZ_HUMAN (286-1087): 7.41e-121: 413: 18.92
+	Hs
		1288623 PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54		HELZ2_HUMAN (298-926): 2.4e-71: 264: 19.62