HitPredict

Interactor 1: TAOK2 (Q6ZQ29)
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2)
Gene: TAOK2

Interactor 2: AFAD (Q9QZQ1)
Afadin (Afadin adherens junction formation factor) (Protein Af-6)
Gene: Afdn

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FHA~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1240 Mm			1 1820
+	Hs
		936316 ROCK1_HUMAN (25-902): 1.39e-153: 498: 17.20		AFAD_HUMAN (1-1820): 0: 1079: 92.98
+	Hs
		692020 MARK3_HUMAN (2-679): 1.07e-151: 476: 15.36		AFAD_HUMAN (1-1820): 0: 1079: 92.98
+	Hs
		936370 MARK2_HUMAN (5-679): 1.31e-143: 456: 15.09		AFAD_HUMAN (1-1820): 0: 1079: 92.98
+	Mm
		1247087 TAOK2_MOUSE (1-1240): 0: 1245: 100.00		NEB2_MOUSE (1002-1144): 2.35e-19: 97.2: 29.80
+	Mm
		999789 TAOK2_MOUSE (1-1240): 0: 1245: 100.00		DLG3_MOUSE (1010-1232): 8.06e-13: 76: 20.08
+	Hs
		1270537 MARK2_HUMAN (5-679): 1.31e-143: 456: 15.09		KI13B_HUMAN (41-681): 5.96e-95: 343: 13.06
+	Hs
		1093109 STK4_HUMAN (24-425): 1.2e-117: 376: 34.38		KIF14_HUMAN (38-681): 1.61e-86: 316: 14.65
+	Hs
		1097668 STK3_HUMAN (15-444): 2.59e-115: 370: 31.66		KIF14_HUMAN (38-681): 1.61e-86: 316: 14.65
+	Hs
		1140969 STK26_HUMAN (23-400): 1.21e-109: 352: 33.59		KIF14_HUMAN (38-681): 1.61e-86: 316: 14.65
+	Dm
		118838 TAO_DROME (1-916): 3.8e-146: 470: 34.83		M9NFI9_DROME (1002-1092): 6.08e-22: 106: 38.95
+	Hs
		692052 MARK3_HUMAN (2-679): 1.07e-151: 476: 15.36		PTN13_HUMAN (978-1122): 1.4e-17: 92.2: 28.48
+	Dm
		119343 Q9VXE3_DROME (26-912): 3.91e-131: 438: 17.12		M9NFI9_DROME (1002-1092): 6.08e-22: 106: 38.95
+	Hs
		1090197 STK26_HUMAN (23-400): 1.21e-109: 352: 33.59		PTN13_HUMAN (978-1122): 1.4e-17: 92.2: 28.48
+	Hs
		138826 STK25_HUMAN (21-421): 1.06e-105: 342: 33.98		PTN13_HUMAN (978-1122): 1.4e-17: 92.2: 28.48
+	Hs
		157397 CTRO_HUMAN (291-944): 1.37e-12: 74.8: 11.78		KIF14_HUMAN (38-681): 1.61e-86: 316: 14.65
+	Mm
		1013688 TNIK_MOUSE (1-305): 3.17e-50: 197: 40.49		DLG2_MOUSE (874-1148): 1.36e-35: 149: 16.47
+	Mm
		999781 TNIK_MOUSE (1-305): 3.17e-50: 197: 40.49		DLG3_MOUSE (1010-1232): 8.06e-13: 76: 20.08
+	Mm
		1013694 TNIK_MOUSE (1-305): 3.17e-50: 197: 40.49		MYO5A_MOUSE (1354-1788): 3.29e-11: 71.1: 8.88
+	Mm
		1000205 ROCK2_MOUSE (458-921): 2.47e-10: 67.5: 8.78		NEB2_MOUSE (1002-1144): 2.35e-19: 97.2: 29.80
+	Hs
		157640 CTRO_HUMAN (291-944): 1.37e-12: 74.8: 11.78		INADL_HUMAN (1003-1089): 2.22e-11: 71.4: 25.81