HitPredict

Interactor 1: CSN2 (Q8W207)
COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Protein FUSCA 12)
Gene: CSN2

Interactor 2: CSN3 (Q8W575)
COP9 signalosome complex subunit 3 (Signalosome subunit 3) (Protein FUSCA 11)
Gene: CSN3

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	12615944, 15703063
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	PCI~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 439 At			1 429
+	Mm
		291845 CSN2_MOUSE (6-437): 5.1e-117: 350: 61.34		CSN3_MOUSE (6-428): 1.09e-116: 349: 37.76
+	Hs
		897331 CSN2_HUMAN (6-437): 5.1e-117: 350: 61.34		CSN3_HUMAN (6-428): 3.09e-116: 347: 37.76
+	Mm
		102341 G3UXW9_MOUSE (11-438): 1.8e-82: 264: 13.96		CSN3_MOUSE (6-428): 1.09e-116: 349: 37.76
+	Hs
		121722 CSN2_HUMAN (6-437): 5.1e-117: 350: 61.34		PSD11_HUMAN (55-393): 6.12e-81: 257: 13.19
+	Dm
		1180707 CSN2_DROME (10-438): 2.24e-113: 341: 59.30		PSD11_DROME (55-394): 6.36e-79: 252: 13.16
+	Hs
		897224 CSN2_HUMAN (6-437): 5.1e-117: 350: 61.34		CSN2_HUMAN (33-384): 4.6e-73: 237: 11.17
+	Hs
		121636 PSD11_HUMAN (29-438): 1.12e-90: 282: 18.62		PSMD3_HUMAN (47-424): 2.86e-96: 300: 20.51
+	Dm
		627126 PSD11_DROME (30-438): 6.75e-86: 270: 18.57		PSMD3_DROME (8-420): 9.69e-100: 308: 19.72
+	Dm
		1277029 CSN2_DROME (10-438): 2.24e-113: 341: 59.30		CSN2_DROME (36-384): 4.86e-68: 224: 12.09
+	Ce
		136319 CSN2_CAEEL (11-413): 2.46e-99: 307: 53.32		CSN3_CAEEL (2-428): 3e-77: 250: 17.28
+	An
		1124313 CSN2_EMENI (4-433): 3.95e-105: 322: 48.50		CSN2_EMENI (37-374): 8.1e-70: 230: 12.43
+	Zm
		6700 A0A1D6E9U1_MAIZE (33-438): 2.26e-87: 274: 19.18		A0A1D6E9U1_MAIZE (8-385): 5.3e-86: 270: 13.70
+	Ce
		136310 CSN2_CAEEL (11-413): 2.46e-99: 307: 53.32		CSN2_CAEEL (30-366): 1.13e-71: 235: 12.46
+	At
		1338954 PSD11_ARATH (36-438): 6.5e-82: 260: 18.83		PSD11_ARATH (8-385): 8.2e-90: 280: 12.66
+	Hs
		121628 PSD11_HUMAN (29-438): 1.12e-90: 282: 18.62		PSD11_HUMAN (55-393): 6.12e-81: 257: 13.19
+	Mm
		102346 G3UXW9_MOUSE (11-438): 1.8e-82: 264: 13.96		CSN2_MOUSE (33-384): 4.6e-73: 237: 11.17
+	Dm
		1277030 CSN2_DROME (10-438): 2.24e-113: 341: 59.30		CSN4_DROME (72-396): 5.67e-44: 159: 11.44
+	Dm
		1180709 PSD11_DROME (30-438): 6.75e-86: 270: 18.57		CSN4_DROME (72-396): 5.67e-44: 159: 11.44