Protein: KCD12
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)

Gene: KCD12, KCTD12
Organism: Homo sapiens
Interactions: 125
UniProt ID: Q96CX2

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0008277 - regulation of G protein-coupled receptor signaling pathway
GO:0042734 - presynaptic membrane
GO:0042802 - identical protein binding
GO:0042995 - cell projection

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1386823

KCD12
BTB/POZ domain-containing protein KCTD12

2

14

Small-scale

0.786

High

1228957

KCD16
BTB/POZ domain-containing protein KCTD16

2

18

High-throughput

0.776

High

1113946

CUL3
Cullin-3

1

20

High-throughput

0.618

High

643019

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

18

High-throughput

0.618

High

981918

RL23
Large ribosomal subunit protein uL14

2

2

High-throughput

0.601

High

1322500

PUSL1
tRNA pseudouridine synthase-like 1

2

0

High-throughput

0.576

High

1257217

KCTD8
BTB/POZ domain-containing protein KCTD8

1

18

High-throughput

0.575

High

1277884

NUFP2
FMR1-interacting protein NUFIP2

2

1

High-throughput

0.571

High

1186354

ZN792
Zinc finger protein 792

2

2

High-throughput

0.553

High

64893

RCCD1
RCC1 domain-containing protein 1

2

2

High-throughput

0.549

High

1199935

P5CR3
Pyrroline-5-carboxylate reductase 3

2

2

High-throughput

0.549

High

1326796

ARG39
Rho guanine nucleotide exchange factor 39

2

10

High-throughput

0.549

High

275989

DUS11
RNA/RNP complex-1-interacting phosphatase

1

2

High-throughput

0.536

High

1013836

RL24
Large ribosomal subunit protein eL24

1

1

High-throughput

0.536

High

1386830

YTHD1
YTH domain-containing family protein 1

1

6

High-throughput

0.536

High

1143464

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.521

High

1228452

FTM
Protein fantom

2

16

High-throughput

0.521

High

1291340

LCA5
Lebercilin

2

16

High-throughput

0.521

High

1386825

OTUB1
Ubiquitin thioesterase OTUB1

2

1

High-throughput

0.521

High

1115352

CUL4B
Cullin-4B

1

20

High-throughput

0.514

High

770409

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.513

High

296860

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

6

Small-scale

0.501

High

214453

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

0

High-throughput

0.493

High

135676

DNM1L
Dynamin-1-like protein

1

4

High-throughput

0.489

High

336230

ZIC2
Zinc finger protein ZIC 2

1

3

High-throughput

0.489

High

349198

LATS1
Serine/threonine-protein kinase LATS1

1

8

High-throughput

0.489

High

484613

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

922480

CLH2
Clathrin heavy chain 2

1

2

High-throughput

0.489

High

948075

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

12

High-throughput

0.489

High

1081610

DYH14
Dynein axonemal heavy chain 14

1

4

High-throughput

0.489

High

1115890

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.489

High

1153011

MYLK
Myosin light chain kinase, smooth muscle

1

8

High-throughput

0.489

High

1386837

TF7L2
Transcription factor 7-like 2

1

6

High-throughput

0.489

High

487625

PARP1
Poly [ADP-ribose] polymerase 1

1

1

Small-scale

0.479

High

609774

LEG3
Galectin-3

1

1

Small-scale

0.479

High

726789

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

2

High-throughput

0.479

High

977328

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.479

High

1033130

EWS
RNA-binding protein EWS

1

7

High-throughput

0.479

High

1102884

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

5

Small-scale

0.479

High

1145317

RNPS1
RNA-binding protein with serine-rich domain 1

1

4

Small-scale

0.479

High

1386845

PA2G4
Proliferation-associated protein 2G4

1

1

Small-scale

0.479

High

155126

SOCS2
Suppressor of cytokine signaling 2

1

8

High-throughput

0.470

High

254638

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.458

High

1088721

SF3A3
Splicing factor 3A subunit 3

1

0

Small-scale

0.458

High

530202

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.445

High

934984

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

1288906

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

14

High-throughput

0.445

High

1386828

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

1

13

Small-scale

0.439

High

106431

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

159792

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.437

High

218611

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.437

High

341642

EYA4
Protein phosphatase EYA4

1

5

High-throughput

0.437

High

443469

CDK1
Cyclin-dependent kinase 1

1

5

Small-scale

0.437

High

474196

NFIC
Nuclear factor 1 C-type

1

6

High-throughput

0.437

High

539226

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

4

Small-scale

0.437

High

589373

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

630333

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.437

High

636879

GSTM3
Glutathione S-transferase Mu 3

1

5

Small-scale

0.437

High

659552

CRCM
Colorectal mutant cancer protein

1

5

High-throughput

0.437

High

696175

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

719166

MPIP1
M-phase inducer phosphatase 1

1

3

High-throughput

0.437

High

719253

MPIP2
M-phase inducer phosphatase 2

1

3

Small-scale

0.437

High

768855

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

883311

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.437

High

888955

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

Small-scale

0.437

High

901475

RAB7A
Ras-related protein Rab-7a

1

4

Small-scale

0.437

High

957995

RAB14
Ras-related protein Rab-14

1

6

Small-scale

0.437

High

1029356

SET
Protein SET

1

2

Small-scale

0.437

High

1045623

TF65
Transcription factor p65

1

5

High-throughput

0.437

High

1085911

TWF1
Twinfilin-1

1

8

Small-scale

0.437

High

1107095

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

1121300

TRI14
Tripartite motif-containing protein 14

1

4

High-throughput

0.437

High

1209494

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.437

High

1254996

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1309474

CEP97
Centrosomal protein of 97 kDa

1

16

Small-scale

0.437

High

1327121

FBXL6
F-box/LRR-repeat protein 6

1

3

High-throughput

0.437

High

1364509

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.437

High

1381484

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

Small-scale

0.437

High

1386826

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

1386833

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.437

High

1386835

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

8

Small-scale

0.437

High

1386839

ATD3A
ATPase family AAA domain-containing protein 3A

1

9

Small-scale

0.437

High

1386841

PD1L1
Programmed cell death 1 ligand 1

1

11

High-throughput

0.437

High

1386844

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

Small-scale

0.437

High

1386846

AKT3
RAC-gamma serine/threonine-protein kinase

1

3

Small-scale

0.437

High

1386848

TRAF6
TNF receptor-associated factor 6

1

11

High-throughput

0.437

High

1386850

MAFB
Transcription factor MafB

1

1

High-throughput

0.437

High

1386847

YBOX2
Y-box-binding protein 2

1

0

High-throughput

0.426

High

225489

CYH3
Cytohesin-3

1

6

High-throughput

0.407

High

942815

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

12

High-throughput

0.407

High

1061273

RHG01
Rho GTPase-activating protein 1

1

6

High-throughput

0.407

High

1153421

CD226
CD226 antigen

1

7

High-throughput

0.407

High

1180950

HFE
Hereditary hemochromatosis protein

1

1

High-throughput

0.407

High

1207249

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

2

High-throughput

0.407

High

1245008

SPSB3
SPRY domain-containing SOCS box protein 3

1

12

High-throughput

0.407

High

1258537

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

3

High-throughput

0.407

High

1349466

F110B
Protein FAM110B

1

3

High-throughput

0.407

High

1386831

RAB34
Ras-related protein Rab-34

1

4

High-throughput

0.407

High

1386849

NGN3
Neurogenin-3

1

1

High-throughput

0.407

High

506704

CTF8
Chromosome transmission fidelity protein 8 homolog

2

0

High-throughput

0.313

High

1164392

TPD53
Tumor protein D53

2

0

High-throughput

0.313

High

1386834

PIF1
ATP-dependent DNA helicase PIF1

2

0

High-throughput

0.313

High

1386843

TSR3
18S rRNA aminocarboxypropyltransferase

2

0

High-throughput

0.313

High

1017557

PRR5
Proline-rich protein 5

1

0

High-throughput

0.279

Low

1124783

NUCG
Endonuclease G, mitochondrial

1

0

High-throughput

0.279

Low

1359825

RASF5
Ras association domain-containing protein 5

1

0

High-throughput

0.279

Low

1386824

NUD16
U8 snoRNA-decapping enzyme

1

0

High-throughput

0.279

Low

301943

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

Small-scale

0.249

Low

380116

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

831216

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

926523

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.249

Low

1289528

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1386827

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low

1386832

ATG5
Autophagy protein 5

1

0

High-throughput

0.249

Low

1386838

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

Small-scale

0.249

Low

67176

ZAR1L
Protein ZAR1-like

1

0

High-throughput

0.232

Low

1260391

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.232

Low

1292397

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.232

Low

1333437

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.232

Low

1386829

SIA7E
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

1

0

High-throughput

0.232

Low

1386836

COPRS
Coordinator of PRMT5 and differentiation stimulator

1

0

High-throughput

0.232

Low

1386840

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.232

Low

1386842

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.232

Low

1386851

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025