HitPredict

Interactor 1: BMAL1 (O00327)
Basic helix-loop-helix ARNT-like protein 1 (Aryl hydrocarbon receptor nuclear translocator-like protein 1) (Basic-helix-loop-helix-PAS protein MOP3) (Brain and muscle ARNT-like 1) (Class E basic helix-loop-helix protein 5) (bHLHe5) (Member of PAS protein 3) (PAS domain-containing protein 3) (bHLH-PAS protein JAP3)
Gene: BMAL1

Interactor 2: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9079689
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 626 Hs			1 732
+	Hs
		431556 ARNT_HUMAN (29-576): 2.06e-151: 457: 33.16		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		432201 EPAS1_HUMAN (64-623): 1.87e-132: 411: 21.83		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		431903 HIF1A_HUMAN (64-623): 1.41e-128: 400: 19.53		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Mm
		432431 HIF1A_MOUSE (62-623): 1.79e-128: 400: 19.71		HS90A_MOUSE (1-732): 0: 1083: 97.82
+	Hs
		438217 HIF1A_HUMAN (64-623): 1.41e-128: 400: 19.53		HS90B_HUMAN (19-732): 0: 1059: 86.13
+	Hs
		431844 SIM2_HUMAN (74-582): 5.54e-118: 367: 21.97		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Mm
		432410 AHR_MOUSE (57-623): 6.93e-115: 364: 20.10		HS90A_MOUSE (1-732): 0: 1083: 97.82
+	Hs
		431737 SIM1_HUMAN (74-544): 3.15e-113: 358: 24.32		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Mm
		432429 SIM1_MOUSE (74-553): 1.08e-111: 354: 24.44		HS90A_MOUSE (1-732): 0: 1083: 97.82
+	Rn
		783943 AHR_RAT (57-623): 2.83e-107: 345: 19.97		HS90A_RAT (1-732): 0: 1085: 97.95
+	Mm
		513659 AHR_MOUSE (57-623): 6.93e-115: 364: 20.10		HS90B_MOUSE (19-732): 0: 1063: 86.98
+	Hs
		438165 SIM2_HUMAN (74-582): 5.54e-118: 367: 21.97		HS90B_HUMAN (19-732): 0: 1059: 86.13
+	Hs
		431594 AHR_HUMAN (57-623): 4.83e-102: 330: 18.34		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		165913 PER2_HUMAN (8-595): 1.65e-98: 328: 16.10		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		432385 HIF3A_HUMAN (62-623): 6.54e-102: 325: 17.79		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		432199 NPAS2_HUMAN (64-618): 1.19e-97: 318: 22.48		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		438468 NPAS1_HUMAN (62-565): 1.44e-104: 330: 19.82		HS90B_HUMAN (19-732): 0: 1059: 86.13
+	Hs
		165921 PER2_HUMAN (8-595): 1.65e-98: 328: 16.10		ENPL_HUMAN (14-701): 0: 898: 46.78
+	Dm
		365490 Q9VXW7_DROME (72-441): 5.8e-22: 102: 26.18		HSP83_DROME (15-732): 0: 1034: 78.41