Interactor 1: Q7K112 (Q7K112)
poly(A)-specific ribonuclease (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase) (Glucose-repressible alcohol dehydrogenase transcriptional effector)
Gene: twin

Interactor 2: Q7K126 (Q7K126)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)
Gene: Not3

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 20504953, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0004535 - poly(A)-specific ribonuclease activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006402 - mRNA catabolic process
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 552
Dm

1 844
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Sc
+ Hs
+ Sp
+ Sp
+ Sc
+ Sc

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Last updated: 11Aug2025