HitPredict

Interactor 1: Q7K148 (Q7K148)
Proteasome subunit beta
Gene: Prosbeta5

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Dm			1 433
+	Dm
		1267694 PSA5_DROME (40-273): 3.61e-89: 266: 17.48		Q7KMQ0_DROME (1-433): 3.94e-145: 422: 100.00
+	Hs
		700565 PSA5_HUMAN (40-272): 3.49e-90: 269: 18.52		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Hs
		701105 PSB5_HUMAN (1-277): 1.25e-88: 266: 51.63		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Sp
		206973 PSA5_SCHPO (40-277): 3.28e-92: 274: 17.27		PRS7_SCHPO (1-430): 4.39e-131: 386: 72.58
+	Dm
		198042 Q7K148_DROME (1-282): 5.99e-99: 292: 100.00		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Sc
		721247 PSB5_YEAST (31-275): 1.42e-89: 269: 52.03		PRS7_YEAST (1-433): 5.55e-128: 379: 67.24
+	Dm
		1264685 Q7K148_DROME (1-282): 5.99e-99: 292: 100.00		Q9V405_DROME (1-425): 2.69e-118: 352: 35.29
+	Dm
		874969 Q7K148_DROME (1-282): 5.99e-99: 292: 100.00		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Dm
		198056 Q8T8V8_DROME (1-282): 1.52e-91: 275: 59.01		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Dm
		1264769 Q7K148_DROME (1-282): 5.99e-99: 292: 100.00		Q9W414_DROME (33-429): 1.46e-116: 347: 42.75
+	Dm
		198060 PSA5_DROME (40-273): 3.61e-89: 266: 17.48		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Hs
		700600 PSA5_HUMAN (40-272): 3.49e-90: 269: 18.52		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		700601 PSA5_HUMAN (40-272): 3.49e-90: 269: 18.52		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Hs
		701129 PSB5_HUMAN (1-277): 1.25e-88: 266: 51.63		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		701130 PSB5_HUMAN (1-277): 1.25e-88: 266: 51.63		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Hs
		700603 PSA5_HUMAN (40-272): 3.49e-90: 269: 18.52		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Dm
		874988 PSA5_DROME (40-273): 3.61e-89: 266: 17.48		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Hs
		700574 PSA5_HUMAN (40-272): 3.49e-90: 269: 18.52		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Sc
		721271 PSB5_YEAST (31-275): 1.42e-89: 269: 52.03		PRS8_YEAST (41-430): 1.24e-115: 346: 45.13
+	Hs
		701110 PSB5_HUMAN (1-277): 1.25e-88: 266: 51.63		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84