Interactor 1: ODPB (Q7K5K3)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (EC 1.2.4.1)
Gene: Pdhb

Interactor 2: Q9W4H6 (Q9W4H6)
Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1)
Gene: Pdha1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.726

The method score is based on:

Property Details
Experiments 14605208, 38944040
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~Transket_pyr, E1_dh~Transketolase_C
Common GO terms GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 365
Dm

1 399
+ Dm
+ Mm
+ Hs
+ At
+ Hs
+ Mm
+ Sc
+ At
+ Ce
+ Hs
+ Ce
+ Ce
+ Sc
+ Gs
+ Tt
+ Pp
+ Mp

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Last updated: 11Aug2025