Protein: ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta)

Gene: ODBB, BCKDHB
Organism: Homo sapiens
Interactions: 45
UniProt ID: P21953

Gene Ontology (top 5):
GO:0003863 - branched-chain 2-oxo acid dehydrogenase activity
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554773

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

6

17

Small-scale

0.953

High

539290

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

2

8

High-throughput

0.811

High

642104

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

5

0

High-throughput

0.688

High

446509

DPOLB
DNA polymerase beta

3

1

High-throughput

0.667

High

642093

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

0

High-throughput

0.602

High

642097

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

143554

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

2

High-throughput

0.536

High

619488

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.536

High

642087

S10A4
Protein S100-A4

1

1

High-throughput

0.536

High

642094

CUL3
Cullin-3

1

2

High-throughput

0.536

High

642095

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

642102

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

642107

SYMM
Methionine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

642113

HDAC6
Protein deacetylase HDAC6

1

3

High-throughput

0.536

High

642115

DPOLL
DNA polymerase lambda

1

1

High-throughput

0.536

High

642103

TTC5
Tetratricopeptide repeat protein 5

1

0

High-throughput

0.513

High

438870

CD1A
T-cell surface glycoprotein CD1a

1

1

High-throughput

0.489

High

642088

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

642090

CEAM8
Cell adhesion molecule CEACAM8

1

2

High-throughput

0.489

High

532355

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

642086

SP100
Nuclear autoantigen Sp-100

1

1

High-throughput

0.479

High

642091

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

642096

PDK1
[Pyruvate dehydrogenase

1

6

High-throughput

0.479

High

642106

OPTN
Optineurin

1

2

High-throughput

0.479

High

642109

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

4

High-throughput

0.479

High

642111

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

642114

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

642117

TRI33
E3 ubiquitin-protein ligase TRIM33

1

6

High-throughput

0.479

High

244923

KATIP
Katanin-interacting protein

1

1

High-throughput

0.445

High

298886

DNJB5
DnaJ homolog subfamily B member 5

1

4

High-throughput

0.437

High

642089

LTK
Leukocyte tyrosine kinase receptor

1

2

High-throughput

0.437

High

642092

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.437

High

642099

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

642116

HECD1
E3 ubiquitin-protein ligase HECTD1

1

4

High-throughput

0.437

High

642110

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.426

High

642098

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.407

High

642100

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.407

High

69760

ZN785
Zinc finger protein 785

2

0

High-throughput

0.328

High

642108

TCF25
Ribosome quality control complex subunit TCF25

2

0

High-throughput

0.328

High

407151

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.279

Low

642101

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.279

Low

642112

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

342103

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

642105

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

2092

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025