HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 189
+	Hs
		203195 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		302274 SC31A_HUMAN (10-495): 1.62e-51: 191: 10.39		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Hs
		297806 K0754_HUMAN (143-499): 5.78e-32: 132: 13.08		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		297829 K0754_HUMAN (143-499): 5.78e-32: 132: 13.08		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		297805 K0754_HUMAN (143-499): 5.78e-32: 132: 13.08		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		195964 PLXB1_HUMAN (277-461): 1.76e-27: 119: 25.82		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		350342 MINK1_HUMAN (269-432): 1.39e-11: 69.2: 22.16		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1070297 MINK1_HUMAN (269-432): 1.39e-11: 69.2: 22.16		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		350405 TITIN_HUMAN (345-474): 5.12e-09: 61.3: 17.56		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		348783 MINK1_HUMAN (269-432): 1.39e-11: 69.2: 22.16		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349478 MINK1_HUMAN (269-432): 1.39e-11: 69.2: 22.16		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914253 TITIN_HUMAN (345-474): 5.12e-09: 61.3: 17.56		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88