HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 747
+	Hs
		370697 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		487837 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		517813 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		NFH_HUMAN (120-629): 9.62e-15: 80.7: 13.33
+	Hs
		1264774 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		370105 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		377539 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90