HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: CD226 (Q15762)
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
Gene: CD226

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Gal-bind_lectin~V-set
Common GO terms	GO:0005178 - integrin binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 336
+	Hs
		127334 LEG8_HUMAN (1-317): 8.01e-137: 392: 100.00		NECT1_HUMAN (4-259): 4.58e-42: 154: 16.01
+	Hs
		127399 LEG8_HUMAN (1-317): 8.01e-137: 392: 100.00		NECT3_HUMAN (8-203): 1.97e-41: 153: 20.10
+	Hs
		127366 LEG8_HUMAN (1-317): 8.01e-137: 392: 100.00		VSIG1_HUMAN (2-334): 2e-36: 137: 14.21
+	Hs
		127350 LEG8_HUMAN (1-317): 8.01e-137: 392: 100.00		CD276_HUMAN (8-262): 5.66e-33: 129: 16.54
+	Hs
		127263 LEG8_HUMAN (1-317): 8.01e-137: 392: 100.00		FGFR1_HUMAN (27-333): 8.9e-14: 74.3: 11.40
+	Hs
		125203 LEG9_HUMAN (3-316): 1.75e-113: 334: 30.83		PVR_HUMAN (17-210): 1.47e-34: 132: 16.06
+	Hs
		125494 LEG9_HUMAN (3-316): 1.75e-113: 334: 30.83		CD276_HUMAN (8-262): 5.66e-33: 129: 16.54
+	Hs
		127292 LEG8_HUMAN (1-317): 8.01e-137: 392: 100.00		VGFR3_HUMAN (35-325): 7.61e-12: 68.5: 11.04
+	Hs
		580728 LEG3_HUMAN (16-153): 1.93e-46: 159: 39.72		PVR_HUMAN (17-210): 1.47e-34: 132: 16.06
+	Hs
		609705 LEG3_HUMAN (16-153): 1.93e-46: 159: 39.72		CD276_HUMAN (8-262): 5.66e-33: 129: 16.54
+	Hs
		480904 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		NECT3_HUMAN (8-203): 1.97e-41: 153: 20.10
+	Hs
		480843 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		VSIG1_HUMAN (2-334): 2e-36: 137: 14.21
+	Hs
		480679 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		PVR_HUMAN (17-210): 1.47e-34: 132: 16.06
+	Hs
		480820 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		CD276_HUMAN (8-262): 5.66e-33: 129: 16.54
+	Hs
		609602 LEG3_HUMAN (16-153): 1.93e-46: 159: 39.72		VGFR3_HUMAN (35-325): 7.61e-12: 68.5: 11.04
+	Hs
		480731 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		VGFR2_HUMAN (25-250): 8.39e-15: 77.4: 14.63
+	Hs
		480730 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		VGFR3_HUMAN (35-325): 7.61e-12: 68.5: 11.04
+	Hs
		480944 LEG1_HUMAN (27-151): 4.33e-38: 133: 28.13		ROBO1_HUMAN (2-231): 6.46e-10: 62.7: 13.36