HitPredict

Interactor 1: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Interactor 2: NET4 (Q9HB63)
Netrin-4 (Beta-netrin) (Hepar-derived netrin-like protein)
Gene: NTN4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 236 Hs			1 628
+	Hs
		517113 NT2NC_HUMAN (69-233): 1.56e-13: 70.1: 32.37		NET4_HUMAN (1-628): 3.13e-149: 446: 100.00
+	Hs
		340703 NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84		NET1_HUMAN (12-628): 1.01e-115: 359: 29.37
+	Hs
		857512 NOTC1_HUMAN (68-233): 8.99e-17: 81.2: 27.84		NET5_HUMAN (109-627): 3.95e-78: 258: 22.71
+	Hs
		1355973 JAG2_HUMAN (8-209): 1.77e-16: 80.1: 31.86		NET5_HUMAN (109-627): 3.95e-78: 258: 22.71
+	Hs
		1047665 NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84		NET5_HUMAN (109-627): 3.95e-78: 258: 22.71
+	Hs
		1355971 NOTC3_HUMAN (12-198): 1.59e-11: 65.5: 29.67		NET5_HUMAN (109-627): 3.95e-78: 258: 22.71
+	Dm
		663795 SLIT_DROME (68-235): 3e-32: 125: 33.14		NETB_DROME (14-231): 9.88e-45: 172: 21.52
+	Dm
		1175444 TENA_DROME (1-159): 3.76e-24: 102: 19.91		NETB_DROME (14-231): 9.88e-45: 172: 21.52
+	Dm
		451766 NOTCH_DROME (10-236): 4.29e-15: 76.2: 21.99		NETB_DROME (14-231): 9.88e-45: 172: 21.52
+	Dm
		262791 TENM_DROME (2-124): 8.67e-15: 75.1: 17.71		NETB_DROME (14-231): 9.88e-45: 172: 21.52
+	Dm
		517393 CRB_DROME (11-180): 9.22e-09: 57.4: 26.37		NETB_DROME (14-231): 9.88e-45: 172: 21.52
+	Hs
		937387 NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84		LAMB2_HUMAN (330-607): 4.83e-14: 77.9: 18.44
+	Hs
		535835 NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84		LAMC1_HUMAN (228-391): 8.08e-11: 67.5: 14.02
+	Hs
		1047538 NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84		LAMB3_HUMAN (330-590): 2.85e-10: 65.6: 16.91
+	Dm
		262858 TENM_DROME (2-124): 8.67e-15: 75.1: 17.71		Q8IP51_DROME (214-399): 6.45e-11: 67.9: 13.44
+	Dm
		451718 NOTCH_DROME (10-236): 4.29e-15: 76.2: 21.99		LAMC1_DROME (201-391): 6.82e-10: 64.5: 15.18
+	Hs
		183243 NOTC2_HUMAN (8-180): 6.98e-16: 78.5: 27.84		LAMA5_HUMAN (205-397): 4.73e-09: 61.8: 16.04
+	Dm
		262790 TENM_DROME (2-124): 8.67e-15: 75.1: 17.71		NETA_DROME (330-483): 3.11e-10: 65.2: 23.98
+	Dm
		451745 NOTCH_DROME (10-236): 4.29e-15: 76.2: 21.99		LAMA_DROME (202-377): 1.27e-09: 63.7: 15.08
+	Dm
		262765 TENM_DROME (2-124): 8.67e-15: 75.1: 17.71		LAMA_DROME (202-377): 1.27e-09: 63.7: 15.08