HitPredict

Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0007165 - signal transduction GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 540 Hs			1 530
+	Hs
		1280375 HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		590324 MUC1_HUMAN (48-468): 4.64e-20: 96.4: 11.72		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367502 YM012_HUMAN (102-539): 3.76e-18: 89.5: 12.81		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1129670 MDC1_HUMAN (79-450): 8.81e-11: 67.1: 13.06		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		925735 SC24C_HUMAN (116-429): 9.68e-11: 66.7: 15.43		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367026 CHAP1_HUMAN (196-539): 3.74e-10: 64.8: 10.09		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367725 PCLO_HUMAN (135-528): 1.21e-09: 63.7: 10.41		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1338263 KMT2C_HUMAN (102-538): 1.41e-09: 63.3: 10.60		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		396419 HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		395433 MUC1_HUMAN (48-468): 4.64e-20: 96.4: 11.72		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		396114 MDC1_HUMAN (79-450): 8.81e-11: 67.1: 13.06		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		396547 KMT2C_HUMAN (102-538): 1.41e-09: 63.3: 10.60		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Mm
		107050 F8VPR5_MOUSE (82-395): 1.46e-11: 69.8: 14.24		ESR1_MOUSE (9-529): 4.9e-134: 403: 43.72
+	Mm
		107054 F8VPR5_MOUSE (82-395): 1.46e-11: 69.8: 14.24		RXRG_MOUSE (13-499): 5.32e-117: 355: 22.56
+	Hs
		833993 KMT2C_HUMAN (102-538): 1.41e-09: 63.3: 10.60		HNF4A_HUMAN (94-502): 1.22e-107: 331: 23.30
+	Mm
		1222856 KMT2C_MOUSE (57-515): 3.5e-09: 62.1: 11.66		ERR2_MOUSE (69-499): 5.29e-107: 328: 31.11
+	Hs
		520168 HUWE1_HUMAN (79-539): 2.9e-23: 106: 13.36		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520042 MDC1_HUMAN (79-450): 8.81e-11: 67.1: 13.06		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520292 CHAP1_HUMAN (196-539): 3.74e-10: 64.8: 10.09		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520207 KMT2C_HUMAN (102-538): 1.41e-09: 63.3: 10.60		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59