Protein: ESR1
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)

Gene: ESR1
Organism: Mus musculus
Interactions: 26
UniProt ID: P19785

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000791 - euchromatin
GO:0001093 - TFIIB-class transcription factor binding
GO:0001222 - transcription corepressor binding
GO:0001223 - transcription coactivator binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625746

NCOA2
Nuclear receptor coactivator 2

1

20

High-throughput

0.621

High

625743

PRGR
Progesterone receptor

1

18

Small-scale

0.618

High

625744

CTNB1
Catenin beta-1

1

20

Small-scale

0.618

High

625747

CNTN2
Contactin-2

1

5

Small-scale

0.553

High

625753

GRIP1
Glutamate receptor-interacting protein 1

1

20

Small-scale

0.552

High

625741

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

14

High-throughput

0.515

High

104405

F6M2J9
Nuclear receptor coactivator-6 beta

1

20

Small-scale

0.501

High

602952

PO4F1
POU domain, class 4, transcription factor 1

1

20

High-throughput

0.481

High

625748

PO4F2
POU domain, class 4, transcription factor 2

1

20

High-throughput

0.481

High

74252

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

107050

F8VPR5
histone acetyltransferase

1

20

Small-scale

0.479

High

109221

G5E884
non-specific serine/threonine protein kinase

1

17

Small-scale

0.479

High

312335

FOXL2
Forkhead box protein L2

1

20

Small-scale

0.479

High

431322

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.479

High

432063

JUN
Transcription factor Jun

1

19

Small-scale

0.479

High

625738

LEF1
Lymphoid enhancer-binding factor 1

1

20

Small-scale

0.479

High

625739

STA5A
Signal transducer and activator of transcription 5A

1

19

Small-scale

0.479

High

625740

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

20

Small-scale

0.479

High

625742

NOS3
Nitric oxide synthase 3

1

4

Small-scale

0.479

High

625745

Q2M4I6
SCAN domain-containing protein 1

1

7

Small-scale

0.479

High

625750

KDM4A
Lysine-specific demethylase 4A

1

20

Small-scale

0.479

High

625751

KDM4C
Lysine-specific demethylase 4C

1

20

Small-scale

0.479

High

625752

KDM4B
Lysine-specific demethylase 4B

1

19

Small-scale

0.479

High

625754

TF7L1
Transcription factor 7-like 1

1

20

Small-scale

0.479

High

236718

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

20

Small-scale

0.457

High

625749

TIF1A
Transcription intermediary factor 1-alpha

1

20

Small-scale

0.457

High


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Last updated: 11Aug2025