HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35031058
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	KH_1~KH_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 463
+	Mm
		904326 IF2B3_MOUSE (1-579): 2.72e-144: 430: 96.55		HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00
+	Mm
		291665 IF2B1_MOUSE (1-577): 5.34e-136: 409: 71.06		HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00
+	Hs
		904173 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Mm
		888797 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00
+	Hs
		128188 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		128357 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00
+	Hs
		128325 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57
+	Hs
		128262 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64
+	Hs
		127935 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57
+	Hs
		1072196 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		1072046 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		1349190 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00
+	Hs
		1294271 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41
+	Mm
		291667 IF2B1_MOUSE (1-577): 5.34e-136: 409: 71.06		Q3TIX6_MOUSE (331-457): 3.14e-11: 67.4: 24.41
+	Xl
		251128 IF23A_XENLA (1-579): 1.82e-136: 411: 77.44		IF23A_XENLA (285-463): 5.6e-09: 60.5: 15.51
+	Hs
		1283856 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64
+	Ce
		954324 HRPK1_CAEEL (160-566): 1.07e-70: 234: 18.54		Q9GRY9_CAEEL (8-224): 1.53e-27: 115: 19.91
+	Mm
		888809 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		IF2B2_MOUSE (272-463): 1.07e-11: 68.9: 14.36
+	Mm
		888806 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		Q3TIX6_MOUSE (331-457): 3.14e-11: 67.4: 24.41