HitPredict

Interactor 1: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Interactor 2: TRI54 (Q9BYV2)
Tripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30)
Gene: TRIM54

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 23414517, 11243782
Identification Methods two hybrid, pull down, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0005737 - cytoplasm
GO:0005874 - microtubule
GO:0007165 - signal transduction
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 353
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024