HitPredict

Interactor 1: RN166 (Q96A37)
E3 ubiquitin-protein ligase RNF166 (EC 2.3.2.27) (RING finger protein 166) (RING-type E3 ubiquitin transferase RNF166)
Gene: RNF166

Interactor 2: RN114 (Q9Y508)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: RNF114

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_UBOX~zf-RING_UBOX, zf_C2HC_14~zf_C2HC_14
Common GO terms GO:0000209 - protein polyubiquitination
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0046872 - metal ion binding
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 237
Hs

1 228
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Last updated: 15 Jul 2024