Protein: RUFY2
RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related)

Gene: RUFY2
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q8WXA3

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0008270 - zinc ion binding
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1360178

RUFY1
RUN and FYVE domain-containing protein 1

5

17

High-throughput

0.927

High

1270813

RUFY3
Protein RUFY3

2

17

High-throughput

0.811

High

1120114

RB33A
Ras-related protein Rab-33A

2

14

High-throughput

0.783

High

1360180

RB33B
Ras-related protein Rab-33B

2

7

High-throughput

0.783

High

1116373

RAB32
Ras-related protein Rab-32

1

15

High-throughput

0.618

High

375779

RASK
GTPase KRas

1

20

High-throughput

0.618

High

630911

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.618

High

1141826

EEA1
Early endosome antigen 1

1

19

High-throughput

0.618

High

1360185

ARL8B
ADP-ribosylation factor-like protein 8B

1

14

High-throughput

0.618

High

1240757

PMF1
Polyamine-modulated factor 1

2

1

High-throughput

0.611

High

482938

TPM1
Tropomyosin alpha-1 chain

3

14

High-throughput

0.609

High

749244

CD70
CD70 antigen

2

1

High-throughput

0.574

High

1210929

CE170
Centrosomal protein of 170 kDa

2

16

High-throughput

0.558

High

901431

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.553

High

901972

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.553

High

957981

RAB14
Ras-related protein Rab-14

1

20

High-throughput

0.553

High

388261

GLPA
Glycophorin-A

2

1

High-throughput

0.549

High

1360188

NPTN
Neuroplastin

2

11

High-throughput

0.549

High

1129253

LAGE3
EKC/KEOPS complex subunit LAGE3

1

1

High-throughput

0.536

High

1147979

SF3B3
Splicing factor 3B subunit 3

1

4

High-throughput

0.508

High

1360179

DUS23
Dual specificity protein phosphatase 23

1

11

High-throughput

0.508

High

249178

DSCAM
Cell adhesion molecule DSCAM

1

6

High-throughput

0.494

High

1322119

SYCE1
Synaptonemal complex central element protein 1

1

3

High-throughput

0.489

High

1353636

LRC15
Leucine-rich repeat-containing protein 15

1

4

High-throughput

0.489

High

278915

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

323502

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

908218

BMX
Cytoplasmic tyrosine-protein kinase BMX

1

13

Small-scale

0.479

High

1113847

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1254833

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1360175

FBXW7
F-box/WD repeat-containing protein 7

1

14

High-throughput

0.479

High

1360186

XPO7
Exportin-7

1

12

High-throughput

0.479

High

1360184

EXOC1
Exocyst complex component 1

1

3

High-throughput

0.457

High

212461

SPIT2
Kunitz-type protease inhibitor 2

1

6

High-throughput

0.445

High

218547

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.445

High

296626

TNF13
Tumor necrosis factor ligand superfamily member 13

1

1

High-throughput

0.445

High

886112

CXCR3
C-X-C chemokine receptor type 3

1

5

High-throughput

0.445

High

934915

TERA
Transitional endoplasmic reticulum ATPase

1

11

High-throughput

0.445

High

1360176

S67A1
Solute carrier family 67 member A1

1

4

High-throughput

0.445

High

1360187

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

1

High-throughput

0.445

High

391151

HEMO
Hemopexin

1

2

High-throughput

0.437

High

1233386

LTOR1
Ragulator complex protein LAMTOR1

1

8

High-throughput

0.437

High

1360174

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.437

High

1360182

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.417

High

133289

P2Y10
Putative P2Y purinoceptor 10

1

10

High-throughput

0.407

High

139281

UPK2
Uroplakin-2

1

1

High-throughput

0.407

High

754076

CD80
T-lymphocyte activation antigen CD80

1

10

High-throughput

0.407

High

1010954

BAT1
b(0,+)-type amino acid transporter 1

1

4

High-throughput

0.407

High

1057690

TNR9
Tumor necrosis factor receptor superfamily member 9

1

8

High-throughput

0.407

High

1101609

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.407

High

1177176

MICB
MHC class I polypeptide-related sequence B

1

3

High-throughput

0.407

High

1240911

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.407

High

1291847

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

8

High-throughput

0.407

High

1293875

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

10

High-throughput

0.407

High

1360177

C170L
Cep170-like protein

1

3

High-throughput

0.407

High

1360181

ZDH11
Palmitoyltransferase ZDHHC11

1

3

High-throughput

0.407

High

1360183

S22AB
Solute carrier family 22 member 11

1

3

High-throughput

0.407

High


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Last updated: 11Aug2025