HitPredict

Interactor 1: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	26451915, 29940186, 26971995, 31371777, 17635994
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology, two hybrid
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 789 Hs			1 1294
+	Hs
		1095848 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYO6_HUMAN (1-1294): 0: 1078: 100.00
+	Hs
		157982 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		MYO6_HUMAN (1-1294): 0: 1078: 100.00
+	Hs
		1123871 DCTN1_HUMAN (173-498): 9.13e-17: 87.3: 18.71		MYO6_HUMAN (1-1294): 0: 1078: 100.00
+	Hs
		1095814 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYO5C_HUMAN (1079-1293): 3.34e-12: 73.8: 10.81
+	Hs
		563008 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYH6_HUMAN (760-1113): 5.52e-10: 66.2: 18.89
+	Hs
		772776 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Hs
		773172 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYH10_HUMAN (762-1135): 7.13e-10: 65.8: 15.54
+	Hs
		556973 MYH4_HUMAN (82-777): 1.52e-24: 112: 11.35		MYH7_HUMAN (740-1206): 6.26e-16: 85.9: 14.08
+	Hs
		562992 MYH6_HUMAN (47-756): 9.84e-24: 110: 9.07		MYH6_HUMAN (760-1113): 5.52e-10: 66.2: 18.89
+	Mm
		1403963 MYO5A_MOUSE (269-660): 6.88e-14: 78: 14.63		MYO5A_MOUSE (712-1170): 2.35e-19: 96.9: 8.28
+	Hs
		157020 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Hs
		157021 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		MYH10_HUMAN (762-1135): 7.13e-10: 65.8: 15.54
+	Hs
		157026 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		MYH11_HUMAN (844-1177): 1.16e-09: 65.5: 18.55
+	Hs
		772645 MYH10_HUMAN (308-731): 6.99e-18: 91.3: 8.67		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Hs
		773110 MYH10_HUMAN (308-731): 6.99e-18: 91.3: 8.67		MYH10_HUMAN (762-1135): 7.13e-10: 65.8: 15.54
+	Hs
		773112 MYH10_HUMAN (308-731): 6.99e-18: 91.3: 8.67		MYH11_HUMAN (844-1177): 1.16e-09: 65.5: 18.55
+	Hs
		772647 MYH11_HUMAN (59-532): 5.02e-15: 82: 10.88		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70
+	Mm
		563088 MYH8_MOUSE (45-494): 1.57e-14: 80.1: 10.99		MYH6_MOUSE (760-1113): 5.61e-10: 66.2: 18.33
+	Hs
		773100 MYO5A_HUMAN (269-660): 1.29e-13: 77.3: 14.15		MYH9_HUMAN (842-1118): 6.27e-10: 66.2: 14.70