HitPredict

Interactor 1: SKAP1 (Q86WV1)
Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)
Gene: SKAP1

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 359 Hs			1 447
+	Hs
		1234944 PKHA7_HUMAN (19-290): 4.09e-36: 141: 14.33		TBL1R_HUMAN (3-260): 2.44e-54: 190: 11.40
+	Hs
		1334178 PKHA5_HUMAN (79-294): 3.11e-33: 132: 16.20		POC1A_HUMAN (223-446): 3.65e-54: 187: 15.56
+	Hs
		1085710 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		TBL3_HUMAN (13-447): 1.82e-58: 206: 13.47
+	Hs
		1419998 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		TBL1R_HUMAN (3-260): 2.44e-54: 190: 11.40
+	Hs
		845350 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		LIS1_HUMAN (3-218): 1.16e-50: 178: 11.86
+	Hs
		1410247 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		TBL1Y_HUMAN (3-258): 7.32e-44: 162: 14.33
+	Hs
		965023 PKHA7_HUMAN (19-290): 4.09e-36: 141: 14.33		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Hs
		302967 PKHA2_HUMAN (23-315): 1.34e-45: 162: 13.20		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Hs
		1387557 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		SNR40_HUMAN (258-447): 4.69e-33: 129: 13.02
+	Hs
		965240 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Hs
		302856 PKHA7_HUMAN (19-290): 4.09e-36: 141: 14.33		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Hs
		284982 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		TAF5L_HUMAN (76-247): 1.77e-26: 114: 15.76
+	Hs
		1235049 PKHA7_HUMAN (19-290): 4.09e-36: 141: 14.33		TBL2_HUMAN (308-446): 4.22e-13: 72.9: 12.10
+	Hs
		302966 PKHA5_HUMAN (79-294): 3.11e-33: 132: 16.20		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Hs
		992962 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30
+	Hs
		1434039 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		NLE1_HUMAN (356-445): 3.96e-18: 88.3: 15.56
+	Hs
		1054139 BTK_HUMAN (105-356): 9.65e-33: 130: 12.72		KTNB1_HUMAN (187-307): 2.22e-09: 61.6: 30.33
+	Hs
		302954 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Hs
		1434331 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		TBL2_HUMAN (308-446): 4.22e-13: 72.9: 12.10
+	Hs
		1415091 PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56		KTNB1_HUMAN (187-307): 2.22e-09: 61.6: 30.33