HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: WIZ (O95785)
Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803)
Gene: WIZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 560 Hs			1 1651
+	Hs
		345030 CDY2_HUMAN (6-288): 5.41e-56: 198: 16.78		WIZ_HUMAN (1-1638): 0: 1483: 100.00
+	Hs
		345024 CDYL_HUMAN (2-288): 4.49e-50: 183: 16.35		WIZ_HUMAN (1-1638): 0: 1483: 100.00
+	Hs
		344930 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		WIZ_HUMAN (1-1638): 0: 1483: 100.00
+	Hs
		129758 CBX4_HUMAN (1-560): 7.61e-163: 477: 100.00		ZN546_HUMAN (554-1252): 2.95e-122: 406: 13.75
+	Hs
		67023 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		ZN729_HUMAN (83-966): 0: 720: 12.48
+	Hs
		70557 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		ZN850_HUMAN (73-663): 1.98e-144: 475: 13.43
+	Hs
		1051147 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		ZNF91_HUMAN (470-1252): 1.91e-132: 445: 13.14
+	Hs
		1394367 MPP8_HUMAN (6-431): 5.27e-87: 289: 13.72		ZN845_HUMAN (754-1252): 8.94e-54: 207: 12.82
+	Hs
		339003 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZN107_HUMAN (719-1252): 6.23e-72: 260: 14.52
+	Hs
		338962 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZN644_HUMAN (696-815): 5.18e-44: 178: 40.95
+	Hs
		1434519 CDY2_HUMAN (6-288): 5.41e-56: 198: 16.78		ZN644_HUMAN (696-815): 5.18e-44: 178: 40.95
+	Hs
		1434511 CDYL_HUMAN (2-288): 4.49e-50: 183: 16.35		ZN644_HUMAN (696-815): 5.18e-44: 178: 40.95
+	Hs
		338826 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZN33A_HUMAN (770-1249): 4.63e-34: 144: 12.87
+	Hs
		338941 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZN184_HUMAN (893-1252): 3.26e-32: 138: 12.67
+	Hs
		338998 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZNF70_HUMAN (334-489): 1.98e-30: 128: 11.32
+	Hs
		338822 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZNF92_HUMAN (348-487): 2.14e-29: 127: 16.90
+	Hs
		338997 CBX6_HUMAN (1-419): 4.7e-61: 209: 24.19		ZN624_HUMAN (104-294): 1.09e-22: 107: 12.44
+	Hs
		1056668 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		ZN33A_HUMAN (770-1249): 4.63e-34: 144: 12.87
+	Hs
		776911 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		ZNF93_HUMAN (332-487): 3.41e-29: 127: 14.97
+	Hs
		585028 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		ZN250_HUMAN (262-453): 5.41e-10: 66.3: 21.89