HitPredict

Interactor 1: AL4A1 (Q8CHT0)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)
Gene: Aldh4a1

Interactor 2: AL4A1 (Q8CHT0)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)
Gene: Aldh4a1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 29222160, 28130547, 22516612
Identification Methods cross-linking study, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Aldedh~Aldedh
Common GO terms GO:0003842 - L-glutamate gamma-semialdehyde dehydrogenase activity
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 562
Mm

1 562
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025