HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35358511, 27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Hs			1 399
+	Hs
		131017 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		849216 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Sc
		768185 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DDI1_YEAST (3-395): 7.99e-93: 287: 30.92
+	Hs
		849244 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		131106 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		131100 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Dm
		1358677 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Zm
		27878 B4FLQ8_MAIZE (1-309): 4.83e-111: 326: 79.29		A0A1D6JMS0_MAIZE (4-241): 2.01e-44: 163: 16.80
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		130790 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		130813 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (6-241): 1.33e-49: 178: 16.53
+	Sc
		797465 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DSK2_YEAST (19-213): 6.83e-31: 123: 15.49
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Sc
		697094 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	Hs
		176966 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		849280 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Dm
		640796 PSMD7_DROME (27-185): 4.64e-35: 131: 23.03		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Hs
		803427 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		849167 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00