Interactor 1: DHX40 (Q8IX18)
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD)
Gene: DHX40

Interactor 2: PRP16 (Q92620)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38)
Gene: DHX38

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 34079125, unassigned3799
Identification Methods proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2_N, DEAD~Helicase_C, HA2_C~HA2_N, HA2_C~Helicase_C, HA2_C~OB_NTP_bind, HA2_N~Helicase_C, HA2_N~OB_NTP_bind, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, OB_NTP_bind~OB_NTP_bind
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005681 - spliceosomal complex
GO:0016887 - ATP hydrolysis activity
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 779
Hs

1 1227
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Ce
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025