HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 8797
+	Hs
		955390 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		SYNE1_HUMAN (1-8797): 0: 1900: 100.00
+	Hs
		1040330 MIRO2_HUMAN (1-618): 0: 795: 100.00		DYST_HUMAN (6586-8703): 3.47e-45: 186: 11.34
+	Hs
		1312275 MIRO2_HUMAN (1-618): 0: 795: 100.00		SPTN5_HUMAN (7500-8769): 3.71e-09: 66.8: 10.55
+	Hs
		581201 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		SYNE2_HUMAN (13-6897): 9.14e-141: 503: 12.40
+	Hs
		955424 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		SYNE2_HUMAN (13-6897): 9.14e-141: 503: 12.40
+	Hs
		174730 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		SPTN2_HUMAN (18-355): 7.97e-49: 197: 39.12
+	Hs
		174731 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		SPTN2_HUMAN (18-355): 7.97e-49: 197: 39.12
+	Hs
		174761 RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70		SPTN2_HUMAN (18-355): 7.97e-49: 197: 39.12
+	Hs
		581002 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		DYST_HUMAN (6586-8703): 3.47e-45: 186: 11.34
+	Hs
		580921 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		UTRN_HUMAN (6294-8769): 2.42e-40: 170: 10.99
+	Hs
		862621 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		UTRN_HUMAN (6294-8769): 2.42e-40: 170: 10.99
+	Hs
		862622 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		UTRN_HUMAN (6294-8769): 2.42e-40: 170: 10.99
+	Hs
		580995 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		SPTB2_HUMAN (128-2193): 3.44e-26: 123: 9.82
+	Hs
		953397 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		SPTB2_HUMAN (128-2193): 3.44e-26: 123: 9.82
+	Hs
		581035 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Hs
		953435 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Hs
		955068 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		SPTB2_HUMAN (128-2193): 3.44e-26: 123: 9.82
+	Hs
		955148 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Hs
		319049 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		K0754_HUMAN (8306-8740): 1.28e-19: 101: 16.51
+	Hs
		319056 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		K0754_HUMAN (8306-8740): 1.28e-19: 101: 16.51