HitPredict

Interactor 1: AMOL1 (Q8IY63)
Angiomotin-like protein 1
Gene: AMOTL1

Interactor 2: HECW2 (Q9P2P5)
E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2)
Gene: HECW2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	27498087, 24163370
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 956 Hs			1 1572
+	Hs
		1454778 AMOL2_HUMAN (92-914): 6.14e-45: 176: 40.12		HECW2_HUMAN (1-1572): 0: 1322: 100.00
+	Hs
		1197115 AMOT_HUMAN (87-890): 6.82e-41: 165: 39.62		HECW2_HUMAN (1-1572): 0: 1322: 100.00
+	Hs
		157945 CTRO_HUMAN (238-841): 1.53e-21: 103: 12.00		HECW2_HUMAN (1-1572): 0: 1322: 100.00
+	Hs
		772879 MYH9_HUMAN (226-951): 6.01e-24: 111: 9.29		HUWE1_HUMAN (1007-1571): 6.06e-165: 557: 30.48
+	Hs
		861678 AMOL1_HUMAN (1-956): 2.83e-155: 484: 100.00		NEDD4_HUMAN (265-596): 3e-21: 103: 10.88
+	Hs
		1314098 AMOL1_HUMAN (1-956): 2.83e-155: 484: 100.00		NED4L_HUMAN (616-1033): 3.07e-17: 90.1: 14.48
+	Hs
		132152 AMOL1_HUMAN (1-956): 2.83e-155: 484: 100.00		WWP2_HUMAN (665-1078): 1.98e-14: 80.8: 16.39
+	Hs
		1314102 AMOL1_HUMAN (1-956): 2.83e-155: 484: 100.00		WWP1_HUMAN (616-1034): 1.14e-13: 78.5: 15.33
+	Hs
		861848 AMOL2_HUMAN (92-914): 6.14e-45: 176: 40.12		NEDD4_HUMAN (265-596): 3e-21: 103: 10.88
+	Hs
		861636 AMOT_HUMAN (87-890): 6.82e-41: 165: 39.62		NEDD4_HUMAN (265-596): 3e-21: 103: 10.88
+	Hs
		132392 AMOL2_HUMAN (92-914): 6.14e-45: 176: 40.12		WWP2_HUMAN (665-1078): 1.98e-14: 80.8: 16.39
+	Hs
		1197064 AMOT_HUMAN (87-890): 6.82e-41: 165: 39.62		NED4L_HUMAN (616-1033): 3.07e-17: 90.1: 14.48
+	Hs
		1430229 AMOL2_HUMAN (92-914): 6.14e-45: 176: 40.12		WWP1_HUMAN (616-1034): 1.14e-13: 78.5: 15.33
+	Hs
		132084 AMOT_HUMAN (87-890): 6.82e-41: 165: 39.62		WWP2_HUMAN (665-1078): 1.98e-14: 80.8: 16.39
+	Hs
		1197083 AMOT_HUMAN (87-890): 6.82e-41: 165: 39.62		WWP1_HUMAN (616-1034): 1.14e-13: 78.5: 15.33
+	Hs
		1197056 AMOT_HUMAN (87-890): 6.82e-41: 165: 39.62		ITCH_HUMAN (166-495): 1.4e-12: 75.1: 12.93
+	Hs
		1106304 ROCK1_HUMAN (418-836): 1.93e-14: 80.1: 10.94		SMUF1_HUMAN (680-902): 1.41e-12: 74.7: 15.19
+	Hs
		587813 DESP_HUMAN (417-798): 5.68e-11: 69.3: 15.63		SMUF1_HUMAN (680-902): 1.41e-12: 74.7: 15.19
+	Hs
		1154155 ITSN1_HUMAN (608-950): 3.15e-09: 63.5: 11.36		ITCH_HUMAN (166-495): 1.4e-12: 75.1: 12.93
+	Hs
		1438992 DAPLE_HUMAN (438-697): 6.1e-09: 62.6: 25.98		SMUF1_HUMAN (680-902): 1.41e-12: 74.7: 15.19