HitPredict

Interactor 1: MAD3 (Q9BW11)
Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx)
Gene: MXD3

Interactor 2: RCOR3 (Q9P2K3)
REST corepressor 3
Gene: RCOR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 206 Hs			1 495
+	Hs
		348119 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		RCOR3_HUMAN (1-495): 1.17e-141: 418: 100.00
+	Hs
		348196 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Mm
		1144973 TFE3_MOUSE (30-177): 8.55e-34: 128: 21.71		MTA2_MOUSE (1-478): 1.74e-92: 297: 15.53
+	Hs
		295907 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		MTA2_HUMAN (1-478): 7.19e-92: 295: 15.71
+	Hs
		346699 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		MTA1_HUMAN (1-433): 2.17e-85: 279: 15.62
+	Mm
		1144911 TFE3_MOUSE (30-177): 8.55e-34: 128: 21.71		MTA1_MOUSE (1-433): 5.29e-85: 278: 15.82
+	Mm
		1144927 TFE3_MOUSE (30-177): 8.55e-34: 128: 21.71		MTA3_MOUSE (1-418): 5.87e-84: 272: 15.45
+	Hs
		898219 MAX_HUMAN (54-164): 5.61e-15: 70.9: 20.72		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		261367 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		NCOR1_HUMAN (35-484): 1.63e-51: 191: 17.04
+	Hs
		348379 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		NCOR2_HUMAN (35-478): 1.59e-48: 182: 18.57
+	Hs
		347852 MYC_HUMAN (26-140): 2.35e-34: 128: 25.00		ZN541_HUMAN (1-268): 7.36e-43: 165: 21.99