Interactor 1: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Interactor 2: ING2 (Q9H160)
Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2)
Gene: ING2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 28514442, 33961781, 16387653
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0070822 - Sin3-type complex
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1048
Hs

1 280
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Last updated: 15 Jul 2024