HitPredict

Interactor 1: TTC9C (Q8N5M4)
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)
Gene: TTC9C

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.694

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TPR_16~TPR_19
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 171 Hs			1 365
+	Hs
		1038732 FKBP4_HUMAN (2-170): 5.52e-35: 128: 23.67		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		124855 AIP_HUMAN (2-171): 1.48e-35: 127: 21.05		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1106143 FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		916727 PPP5_HUMAN (2-163): 3.11e-30: 116: 14.20		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Mm
		1221333 PPP5_MOUSE (2-163): 8.89e-31: 117: 14.82		SGT1_MOUSE (1-365): 6.5e-76: 239: 77.99
+	Hs
		76515 FKBP4_HUMAN (2-170): 5.52e-35: 128: 23.67		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Dm
		1478357 FKB59_DROME (2-170): 6.85e-35: 128: 20.71		Q9VJD4_DROME (9-226): 1.39e-47: 165: 17.73
+	Dm
		1475666 FKB59_DROME (2-170): 6.85e-35: 128: 20.71		Q9VH81_DROME (4-218): 1.06e-39: 149: 13.58
+	Ps
		1444869 TOC64_PEA (6-156): 1.77e-32: 123: 18.54		TOC64_PEA (8-127): 5.55e-39: 148: 21.67
+	Hs
		916653 FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Mm
		1221303 PPP5_MOUSE (2-163): 8.89e-31: 117: 14.82		PPP5_MOUSE (9-249): 1.45e-39: 148: 14.69
+	Hs
		916630 PPP5_HUMAN (2-163): 3.11e-30: 116: 14.20		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Hs
		1106073 FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		1125666 FKBP8_HUMAN (2-171): 1.4e-30: 116: 26.47		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		185622 FKBP4_HUMAN (2-170): 5.52e-35: 128: 23.67		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Dm
		1480500 FKB59_DROME (2-170): 6.85e-35: 128: 20.71		Q9VPN5_DROME (1-321): 9.81e-18: 86: 10.98
+	Hs
		185664 FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		185549 PPP5_HUMAN (2-163): 3.11e-30: 116: 14.20		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		185693 FKBP8_HUMAN (2-171): 1.4e-30: 116: 26.47		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		318008 FKBP5_HUMAN (2-170): 4.62e-33: 123: 21.30		TOM70_HUMAN (5-278): 4.48e-12: 69.1: 10.07