Interactor 1: TRIMM (Q8N7C3)
Probable E3 ubiquitin-protein ligase TRIML2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIML2) (SPRY domain-containing protein 6) (Tripartite motif family-like protein 2)
Gene: TRIML2
Interactor 2: TRI54 (Q9BYV2)
Tripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30)
Gene: TRIM54
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.783 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX |
| Common GO terms | GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0045087 - innate immune response GO:0061630 - ubiquitin protein ligase activity |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
