HitPredict

Interactor 1: EAF6 (Q9HAF1)
Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) (hEAF6) (Sarcoma antigen NY-SAR-91)
Gene: MEAF6

Interactor 2: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.731

The method score is based on:

Property Details
Experiments 28514442, 33961781, 26186194, 30833792, 32296183, 24981860
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000123 - histone acetyltransferase complex
GO:0001558 - regulation of cell growth
GO:0005654 - nucleoplasm
GO:0006275 - regulation of DNA replication
GO:0006355 - regulation of DNA-templated transcription
and 2 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 191
Hs

1 790
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024