HitPredict

Interactor 1: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 3159
+	Hs
		1380090 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		EP400_HUMAN (1-3159): 0: 1359: 100.00
+	Hs
		1387495 SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04		EP400_HUMAN (1-3159): 0: 1359: 100.00
+	Hs
		703356 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Hs
		703359 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Hs
		1132879 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Hs
		142376 PEX7_HUMAN (49-333): 2.45e-59: 196: 17.36		CHD5_HUMAN (1543-2521): 7.27e-162: 557: 13.46
+	Hs
		703360 SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Hs
		1132932 GRWD1_HUMAN (68-330): 3.43e-56: 192: 15.84		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Hs
		1186497 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		CHD9_HUMAN (1564-2538): 1.63e-137: 487: 12.82
+	Hs
		1338981 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		CHD8_HUMAN (1505-2480): 7.13e-134: 475: 12.52
+	Hs
		964955 WDR5_HUMAN (7-245): 2.41e-38: 141: 11.84		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Hs
		965260 WDR5_HUMAN (7-245): 2.41e-38: 141: 11.84		CHD8_HUMAN (1505-2480): 7.13e-134: 475: 12.52
+	Hs
		1339030 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		INO80_HUMAN (1754-2150): 3.7e-83: 306: 25.38
+	Hs
		965325 WDR5_HUMAN (7-245): 2.41e-38: 141: 11.84		INO80_HUMAN (1754-2150): 3.7e-83: 306: 25.38
+	Hs
		1338959 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		SMRCD_HUMAN (1895-2052): 1.86e-24: 115: 38.27
+	Hs
		1253855 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		SRCAP_HUMAN (2495-3157): 8.56e-17: 90.5: 14.40
+	Hs
		903421 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Hs
		903450 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Hs
		1387556 SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04		SMRCD_HUMAN (1895-2052): 1.86e-24: 115: 38.27
+	Hs
		903453 SNR40_HUMAN (249-378): 5.59e-25: 106: 17.04		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62