Protein: INO80
Chromatin-remodeling ATPase INO80 (hINO80) (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) (INO80 complex subunit A)

Gene: INO80
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q9ULG1

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0003677 - DNA binding
GO:0003779 - actin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1437053

ARP5
Actin-related protein 5

8

20

Small-scale

0.970

High

1461555

RUVB2
RuvB-like 2

7

20

Small-scale

0.962

High

1461556

RUVB1
RuvB-like 1

7

20

Small-scale

0.960

High

1436854

ARP8
Actin-related protein 8

7

20

Small-scale

0.954

High

1420628

IN80B
INO80 complex subunit B

5

0

Small-scale

0.865

High

980527

H4
Histone H4

3

17

Small-scale

0.817

High

953175

ACTB
Actin, cytoplasmic 1

2

20

Small-scale

0.789

High

675722

TYY1
Transcriptional repressor protein YY1

8

13

Small-scale

0.757

High

1461557

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

7

2

Small-scale

0.745

High

1242506

NFRKB
Nuclear factor related to kappa-B-binding protein

6

4

Small-scale

0.730

High

1390189

MCRS1
Microspherule protein 1

6

3

Small-scale

0.724

High

1334372

IN80E
INO80 complex subunit E

7

0

Small-scale

0.712

High

1200565

IN80D
INO80 complex subunit D

5

1

Small-scale

0.706

High

317383

ACL6B
Actin-like protein 6B

1

20

High-throughput

0.691

High

993018

RACK1
Small ribosomal subunit protein RACK1

1

17

High-throughput

0.691

High

503679

TFPT
TCF3 fusion partner

5

0

Small-scale

0.676

High

1244688

IN80C
INO80 complex subunit C

3

3

Small-scale

0.656

High

965325

WDR5
WD repeat-containing protein 5

3

15

Small-scale

0.633

High

1196921

BCL7A
B-cell CLL/lymphoma 7 protein family member A

2

10

High-throughput

0.628

High

1357482

BCL7C
B-cell CLL/lymphoma 7 protein family member C

2

10

High-throughput

0.628

High

346485

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.618

High

355321

ACL6A
Actin-like protein 6A

1

20

Small-scale

0.618

High

419268

H2A1B
Histone H2A type 1-B/E

1

20

High-throughput

0.618

High

1017292

H33
Histone H3.3

1

20

High-throughput

0.618

High

1162923

H2A2C
Histone H2A type 2-C

1

20

Small-scale

0.618

High

1314884

FANCM
Fanconi anemia group M protein

1

16

Small-scale

0.618

High

1339030

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

1353065

GEMI5
Gem-associated protein 5

1

9

High-throughput

0.618

High

260601

BRD4
Bromodomain-containing protein 4

2

20

High-throughput

0.584

High

1141355

BRD3
Bromodomain-containing protein 3

2

20

High-throughput

0.584

High

1364676

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

2

Small-scale

0.584

High

397196

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1157989

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.565

High

224826

ACTN4
Alpha-actinin-4

1

4

Small-scale

0.561

High

1436624

PKHF2
Pleckstrin homology domain-containing family F member 2

2

4

High-throughput

0.553

High

785525

RL4
Large ribosomal subunit protein uL4

1

5

High-throughput

0.536

High

827519

MLH1
DNA mismatch repair protein Mlh1

1

1

High-throughput

0.536

High

1127534

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.489

High

1331638

LRTM2
Leucine-rich repeat and transmembrane domain-containing protein 2

1

3

High-throughput

0.489

High

129541

MEN1
Menin

1

6

High-throughput

0.479

High

143321

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

162732

ANM5
Protein arginine N-methyltransferase 5

1

7

Small-scale

0.479

High

243270

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

339888

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

474365

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

482169

RET1
Retinol-binding protein 1

1

3

High-throughput

0.479

High

487871

PARP1
Poly [ADP-ribose] polymerase 1

1

20

Small-scale

0.479

High

538102

HSP7C
Heat shock cognate 71 kDa protein

1

7

Small-scale

0.479

High

538489

EGR2
E3 SUMO-protein ligase EGR2

1

5

High-throughput

0.479

High

590012

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

674373

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

696842

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.479

High

739044

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

761926

HSP74
Heat shock 70 kDa protein 4

1

15

Small-scale

0.479

High

769491

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

905279

MECP2
Methyl-CpG-binding protein 2

1

20

High-throughput

0.479

High

996894

TBA1B
Tubulin alpha-1B chain

1

9

Small-scale

0.479

High

1005993

GTF2I
General transcription factor II-I

1

1

High-throughput

0.479

High

1033814

PO5F1
POU domain, class 5, transcription factor 1

1

17

High-throughput

0.479

High

1088093

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1118695

KLF9
Krueppel-like factor 9

1

19

High-throughput

0.479

High

1133730

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1141023

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1152759

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1259567

TBA1A
Tubulin alpha-1A chain

1

9

Small-scale

0.479

High

1352827

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1367566

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1383416

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

1

High-throughput

0.479

High

1405652

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1405747

KLF6
Krueppel-like factor 6

1

20

High-throughput

0.479

High

1458647

LHX3
LIM/homeobox protein Lhx3

1

13

High-throughput

0.479

High

1459281

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1461554

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

Small-scale

0.479

High

1058720

CKAP4
Cytoskeleton-associated protein 4

1

15

High-throughput

0.470

High

1445939

RAB18
Ras-related protein Rab-18

1

2

High-throughput

0.445

High

1434210

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.437

High

127206

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

1449195

CAH10
Carbonic anhydrase-related protein 10

3

0

High-throughput

0.347

High


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Last updated: 11Aug2025