HitPredict

Interactor 1: VP601 (Q9LPN5)
Vacuolar protein sorting-associated protein 60.1
Gene: VPS60-1

Interactor 2: VPS4 (Q9ZNT0)
Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1 (AtSKD1) (EC 3.6.4.6) (Protein VACUOLAR PROTEIN SORTING 4)
Gene: SKD1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22639582
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005771 - multivesicular body GO:0015031 - protein transport GO:0032585 - multivesicular body membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 235 At			1 435
+	At
		98409 F4JXR3_ARATH (1-235): 1.91e-62: 198: 75.00		VPS4_ARATH (1-435): 1.73e-129: 382: 100.00
+	Hs
		1349476 CHMP5_HUMAN (1-231): 7.2e-43: 146: 42.67		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	At
		1352475 VPS2A_ARATH (1-208): 5.73e-33: 120: 18.69		VPS4_ARATH (1-435): 1.73e-129: 382: 100.00
+	Hs
		260159 CHMP5_HUMAN (1-231): 7.2e-43: 146: 42.67		VPS4B_HUMAN (2-435): 1.76e-117: 352: 53.02
+	Hs
		1286748 CHM4C_HUMAN (1-230): 3.77e-37: 131: 19.40		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Hs
		1330555 CHM4B_HUMAN (15-224): 2.71e-34: 124: 19.52		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Dm
		1374793 CHMP5_DROME (1-231): 1.28e-41: 143: 42.13		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Hs
		1316087 CHM4A_HUMAN (1-229): 9.87e-33: 119: 18.34		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Zm
		14117 A0A1D6P3C0_MAIZE (61-224): 3.49e-35: 128: 24.39		A0A1D6G1D0_MAIZE (107-433): 7.2e-115: 348: 43.84
+	Hs
		208869 CHM2A_HUMAN (1-185): 1.93e-28: 108: 17.80		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Dm
		1249824 CHM4_DROME (2-220): 2.1e-35: 127: 20.00		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Hs
		208804 CHM2A_HUMAN (1-185): 1.93e-28: 108: 17.80		VPS4B_HUMAN (2-435): 1.76e-117: 352: 53.02
+	Sc
		857408 VPS20_YEAST (6-225): 1.79e-31: 116: 22.17		VPS4_YEAST (2-435): 1.23e-113: 342: 53.30
+	Sc
		732854 DID4_YEAST (7-223): 1.81e-30: 114: 13.76		VPS4_YEAST (2-435): 1.23e-113: 342: 53.30
+	Sc
		764863 SNF7_YEAST (3-214): 1.33e-29: 112: 16.90		VPS4_YEAST (2-435): 1.23e-113: 342: 53.30
+	Hs
		913333 CHM4C_HUMAN (1-230): 3.77e-37: 131: 19.40		PRS10_HUMAN (8-383): 1.3e-105: 319: 25.97
+	Hs
		875207 CHM4C_HUMAN (1-230): 3.77e-37: 131: 19.40		TERA_HUMAN (113-433): 8.32e-78: 259: 27.76
+	Hs
		875313 CHM4B_HUMAN (15-224): 2.71e-34: 124: 19.52		TERA_HUMAN (113-433): 8.32e-78: 259: 27.76
+	Hs
		1330534 CHM4B_HUMAN (15-224): 2.71e-34: 124: 19.52		SPAST_HUMAN (77-355): 1.12e-62: 214: 44.06
+	Hs
		208865 CHM2A_HUMAN (1-185): 1.93e-28: 108: 17.80		SPAST_HUMAN (77-355): 1.12e-62: 214: 44.06