HitPredict

Interactor 1: Q9N6D8 (Q9N6D8)
GH11591p (Transcription factor) (p53 tumor suppressor-like protein) (p53, isoform A) (p53, isoform C) (p53-like regulator of apoptosis and cell cycle)
Gene: p53

Interactor 2: TOPRS (Q9V8P9)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (dTopors)
Gene: Topors

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	14871887, 15710747
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 385 Dm			1 1038
+	Dm
		1213222 Q8IMZ4_DROME (12-385): 0: 599: 99.47		TOPRS_DROME (1-1038): 0: 1279: 100.00
+	Hs
		387590 P53_HUMAN (75-316): 6.34e-103: 311: 21.51		TOPRS_HUMAN (95-661): 4.16e-146: 465: 24.91
+	Mm
		356873 P53_MOUSE (26-316): 3.31e-111: 332: 20.70		TOPRS_MOUSE (95-661): 8.58e-137: 440: 24.27
+	Dm
		1341789 Q9N6D8_DROME (1-385): 0: 617: 100.00		Q9VNE0_DROME (59-248): 2.81e-30: 132: 15.63
+	Dm
		1213227 Q8IMZ4_DROME (12-385): 0: 599: 99.47		Q9VNE0_DROME (59-248): 2.81e-30: 132: 15.63