HitPredict

Interactor 1: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 671 Hs			1 1824
+	Hs
		298964 SRBS2_HUMAN (56-671): 2.3e-57: 212: 26.28		AFAD_HUMAN (1-1824): 0: 1279: 100.00
+	Hs
		876493 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		AFAD_HUMAN (1-1824): 0: 1279: 100.00
+	Hs
		298982 SRBS2_HUMAN (56-671): 2.3e-57: 212: 26.28		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Mm
		1113245 SRBS2_MOUSE (56-671): 5.81e-63: 229: 27.24		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		1256281 SH3R3_HUMAN (81-579): 2.19e-16: 85.4: 11.58		KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64
+	Hs
		1052200 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		1066628 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Rn
		192745 SRBS2_RAT (56-671): 3.74e-63: 229: 27.36		SYJ2B_RAT (1001-1098): 1.79e-20: 91.4: 33.00
+	Mm
		1143326 SRBS1_MOUSE (88-671): 6.32e-41: 162: 25.89		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Mm
		561163 SPTN1_MOUSE (180-622): 2.42e-38: 155: 15.27		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		231661 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66
+	Dm
		113458 Q9VIF7_DROME (44-520): 1.75e-30: 130: 16.56		M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95
+	Mm
		1143413 SH3R3_MOUSE (237-603): 4.08e-16: 84.6: 12.03		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Mm
		1143451 SH3K1_MOUSE (614-671): 2.08e-13: 75.5: 25.86		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		1052346 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		NEB1_HUMAN (1002-1092): 1.04e-19: 98.7: 40.00
+	Hs
		275210 GRAP2_HUMAN (182-436): 9.34e-19: 90.1: 12.83		LNX2_HUMAN (908-1089): 8.99e-18: 91.8: 18.13
+	Hs
		1020196 SH3R3_HUMAN (81-579): 2.19e-16: 85.4: 11.58		PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14
+	Hs
		1052325 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60
+	Hs
		1052360 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		MYO5A_HUMAN (1369-1800): 2.36e-11: 71.5: 10.74
+	Hs
		1052202 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67