HitPredict

Interactor 1: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 2896
+	Hs
		1302925 SIR7_HUMAN (1-400): 0: 535: 100.00		MINT_HUMAN (22-1891): 2.31e-43: 178: 9.12
+	Hs
		1311999 SIR7_HUMAN (1-400): 0: 535: 100.00		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		821054 SIR7_HUMAN (1-400): 0: 535: 100.00		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		1344539 SIR7_HUMAN (1-400): 0: 535: 100.00		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		1127708 SIR7_HUMAN (1-400): 0: 535: 100.00		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Hs
		1170068 SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87		SRCAP_HUMAN (1722-2034): 1.11e-09: 67: 20.93
+	Hs
		1127669 SIR1_HUMAN (78-380): 5.06e-78: 257: 19.94		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Mm
		1265847 SIR1_MOUSE (78-380): 5.54e-78: 256: 19.94		NCOR2_MOUSE (1109-2884): 1.02e-09: 66.7: 8.66