HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: NRCAM (Q92823)
Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)
Gene: NRCAM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	22889411
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 1304
+	Mm
		1283506 DLG1_MOUSE (432-728): 6.43e-36: 147: 19.60		NRCAM_MOUSE (1-1304): 0: 846: 89.88
+	Mm
		1223607 DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88		NRCAM_MOUSE (1-1304): 0: 846: 89.88
+	Hs
		249172 LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		1279321 LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00		SDK1_HUMAN (130-1302): 9.06e-82: 298: 16.22
+	Hs
		249130 DLG1_HUMAN (477-728): 1.31e-31: 134: 21.88		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		249128 PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		249118 DLG4_HUMAN (581-725): 1.82e-22: 104: 22.88		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		249141 DLG2_HUMAN (139-639): 7.84e-22: 103: 11.49		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		249164 MAGI2_HUMAN (94-504): 6.37e-19: 94: 10.17		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		249149 MAGI3_HUMAN (320-722): 2.19e-17: 89.4: 13.52		DSCAM_HUMAN (3-1164): 1.14e-108: 381: 15.86
+	Hs
		1288686 MAGI2_HUMAN (94-504): 6.37e-19: 94: 10.17		DSCL1_HUMAN (17-1190): 2.4e-101: 359: 14.89
+	Mm
		558530 DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88		CNTN1_MOUSE (4-944): 6.48e-96: 333: 16.00
+	Rn
		92890 DLG3_RAT (234-594): 1.38e-37: 152: 19.95		D3ZDA6_RAT (477-1212): 2.29e-58: 224: 14.89
+	Rn
		92885 D3ZWS0_RAT (358-722): 2.2e-27: 121: 17.74		D3ZDA6_RAT (477-1212): 2.29e-58: 224: 14.89
+	Rn
		92888 DLG4_RAT (581-725): 1.72e-22: 104: 22.88		D3ZDA6_RAT (477-1212): 2.29e-58: 224: 14.89
+	Rn
		92891 DLG2_RAT (139-499): 7.18e-21: 100: 12.12		D3ZDA6_RAT (477-1212): 2.29e-58: 224: 14.89
+	Rn
		92887 MAGI2_RAT (141-381): 1.36e-17: 89.7: 11.62		D3ZDA6_RAT (477-1212): 2.29e-58: 224: 14.89
+	Mm
		999930 DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88		DCC_MOUSE (662-1181): 1.37e-25: 117: 10.67
+	Hs
		1353235 PARD3_HUMAN (247-554): 1.4e-32: 137: 20.96		TITIN_HUMAN (946-1174): 1.77e-10: 68.2: 9.61
+	Mm
		1223570 DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88		SDK2_MOUSE (736-1178): 1.34e-18: 94.8: 9.87