HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 29121065, 32296183, unassigned1654, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~fn3, zf-B_box~zf-C3HC4
Common GO terms GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 728
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Service provided by Combinatics, Japan

Last updated: 11Aug2025