HitPredict

Interactor 1: NLK (Q9U9Y8)
Serine/threonine kinase NLK (EC 2.7.11.24) (Loss of intestine protein 1) (Nemo-like kinase)
Gene: lit-1

Interactor 2: NLK (Q9U9Y8)
Serine/threonine kinase NLK (EC 2.7.11.24) (Loss of intestine protein 1) (Nemo-like kinase)
Gene: lit-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 25548171, 10380924, 10488343
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0001714 - endodermal cell fate specification
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
and 20 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 634
Ce

1 634
+ Dm
+ Hs
+ Hs
+ At
+ Hs
+ At
+ At
+ At
+ At
+ Zm
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs

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Last updated: 15 Jul 2024