Interactor 1: HEM1 (Q8VC19)
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)
Gene: Alas1

Interactor 2: HEM1 (Q8VC19)
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)
Gene: Alas1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29222160
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_1_2~Aminotran_1_2
Common GO terms GO:0001666 - response to hypoxia
GO:0003870 - 5-aminolevulinate synthase activity
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
and 18 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 642
Mm

1 642
+ Hs
+ Mm
+ Hs
+ Hs
+ At
+ Dm
+ Sc
+ Sc
+ Ec
+ Sc
+ Hs
+ At
+ Sp
+ Ec
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025