Interactor 1: NALP7 (Q8WX94)
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)
Gene: NLRP7
Interactor 2: NALP7 (Q8WX94)
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)
Gene: NLRP7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.42 | 1.00 | 0.653 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25082979 |
| Identification Methods | two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_6~LRR_6, LRR_6~NACHT, NACHT~NACHT, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD2~NOD2_WH, PYRIN~PYRIN |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0010955 - negative regulation of protein processing GO:0019828 - aspartic-type endopeptidase inhibitor activity GO:0019966 - interleukin-1 binding and 6 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
