HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: PHF19 (Q9CXG9)
PHD finger protein 19 (Polycomb-like protein 3)
Gene: PHF19

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23104054, 22438827
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0035098 - ESC/E(Z) complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 578
+	Hs
		285328 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		PHF19_HUMAN (1-578): 0: 841: 88.79
+	Mm
		1036639 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		MTF2_MOUSE (8-576): 0: 722: 45.02
+	Hs
		285539 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		MTF2_HUMAN (8-576): 0: 708: 44.85
+	Hs
		210225 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		PHF1_HUMAN (34-574): 0: 651: 41.22
+	Dm
		1174295 Q9VKD5_DROME (1-440): 5.53e-78: 251: 49.89		PCL_DROME (38-561): 1.22e-136: 425: 24.73
+	Dm
		1173868 ESC_DROME (23-226): 4.37e-10: 63.5: 8.10		PCL_DROME (38-561): 1.22e-136: 425: 24.73
+	Hs
		965248 WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09		CSR2B_HUMAN (199-535): 4.89e-106: 338: 22.22
+	Dm
		1375063 WDS_DROME (181-441): 2.05e-48: 170: 15.21		ASH2_DROME (184-450): 2.77e-69: 235: 18.28
+	Mm
		965400 WDR5_MOUSE (335-440): 3.34e-14: 75.4: 15.09		CSR2B_MOUSE (199-535): 2.88e-100: 322: 22.78
+	Dm
		1463911 WDS_DROME (181-441): 2.05e-48: 170: 15.21		Q9VJ73_DROME (182-430): 5.91e-61: 217: 18.12
+	Hs
		1380227 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		ASH2L_HUMAN (149-423): 4.78e-82: 270: 15.25
+	Hs
		1291948 WDR5B_HUMAN (279-439): 1.91e-20: 93.5: 12.27		ASH2L_HUMAN (149-423): 4.78e-82: 270: 15.25
+	Hs
		965302 WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09		ASH2L_HUMAN (149-423): 4.78e-82: 270: 15.25