HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: MED28 (Q9H204)
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Gene: MED28

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16964398
Identification Methods	affinity chromatography technology, peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 178
+	Hs
		1054144 BTK_HUMAN (551-727): 1.81e-31: 132: 20.65		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		840985 ABL2_HUMAN (545-725): 4.18e-31: 132: 25.28		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		440724 FYN_HUMAN (556-721): 1.88e-31: 131: 20.69		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		840897 TEC_HUMAN (390-727): 3.86e-31: 131: 14.40		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		440205 LCK_HUMAN (520-724): 1.6e-30: 128: 21.03		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		463220 YES_HUMAN (556-728): 4.11e-30: 127: 19.34		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		473472 HCK_HUMAN (551-724): 3.56e-30: 127: 22.53		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		557467 SRC_HUMAN (535-728): 2.75e-28: 122: 18.81		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Mm
		813528 FYN_MOUSE (556-721): 1.88e-31: 131: 20.69		MED28_MOUSE (1-178): 8.49e-99: 284: 94.38
+	Hs
		699851 P85A_HUMAN (606-721): 3.8e-21: 100: 28.81		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		987933 GRB2_HUMAN (329-411): 1.46e-14: 75.2: 31.40		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00