HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 1085
+	Hs
		1364895 P55G_HUMAN (313-722): 1.49e-99: 316: 72.02		S12A4_HUMAN (1-1085): 0: 1170: 100.00
+	Hs
		463841 LYN_HUMAN (527-724): 1.29e-29: 125: 18.78		S12A4_HUMAN (1-1085): 0: 1170: 100.00
+	Hs
		913684 VAV2_HUMAN (561-717): 1.36e-31: 134: 21.18		S12A6_HUMAN (7-1085): 0: 1100: 76.43
+	Hs
		463825 LYN_HUMAN (527-724): 1.29e-29: 125: 18.78		S12A6_HUMAN (7-1085): 0: 1100: 76.43
+	Hs
		463869 LYN_HUMAN (527-724): 1.29e-29: 125: 18.78		S12A7_HUMAN (1-1085): 0: 1056: 69.05
+	Hs
		440465 FYN_HUMAN (556-721): 1.88e-31: 131: 20.69		S12A2_HUMAN (37-1085): 0: 744: 21.39
+	Hs
		440008 LCK_HUMAN (520-724): 1.6e-30: 128: 21.03		S12A2_HUMAN (37-1085): 0: 744: 21.39
+	Hs
		463420 LYN_HUMAN (527-724): 1.29e-29: 125: 18.78		S12A2_HUMAN (37-1085): 0: 744: 21.39
+	Dm
		362522 SRC64_DROME (550-722): 5.57e-33: 136: 18.23		Q9VNP7_DROME (162-635): 2.29e-91: 306: 14.26
+	Hs
		463414 LYN_HUMAN (527-724): 1.29e-29: 125: 18.78		CTR2_HUMAN (161-603): 3.4e-90: 305: 15.99
+	Hs
		463061 YES_HUMAN (556-728): 4.11e-30: 127: 19.34		LAT1_HUMAN (162-687): 2.34e-77: 265: 13.65
+	Hs
		463460 LYN_HUMAN (527-724): 1.29e-29: 125: 18.78		LAT1_HUMAN (162-687): 2.34e-77: 265: 13.65
+	Hs
		211105 FYN_HUMAN (556-721): 1.88e-31: 131: 20.69		CTR4_HUMAN (164-601): 7.51e-31: 131: 14.09
+	Hs
		211106 YES_HUMAN (556-728): 4.11e-30: 127: 19.34		CTR4_HUMAN (164-601): 7.51e-31: 131: 14.09